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Small Business: The Hunt For Affordable Health Insurance
"For entrepreneurs trying to start or run a business, the obstacles are huge. But few loom as large as one: health care," the Wall Street Journal reports. "At some businesses, in fact, health care is the highest expense after salaries - with devastating consequences. Owners must skimp on vital investments like marketing and research. Some can"t hire the people they want because top candidates demand premium coverage. Or they end up understaffed because of the high cost of insurance - and lose potential clients as a result. At the same time, to keep costs in check, countless companies are slashing coverage or dropping it entirely. Some are turning to freelancers or offshore workers instead of hiring full-timers and locals. And some would-be entrepreneurs find insurance so onerous that they"re not even starting a business in the first place."

Surgery No Better Than Drugs For Heart Disease Survival In Diabetes Patients
An international landmark study found that death rates for patients with both type 2 diabetes and heart disease was the same whether they received
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Sciele Pharma Announces Availability Of Ulesfia (Benzyl Alcohol Lotion 5%), First Prescription Non-Neurotoxic Head Lice Treatment
Sciele Pharma, Inc., a Shionogi Company, announced the availability of Ulesfia (Benzyl Alcohol Lotion 5%), the first and only prescription medication that kills head lice by asphyxiation without potential neurotoxic side effects. Approved by the U.S. Food & Drug Administration (FDA), Ulesfia is indicated for the topical treatment of head lice infestation in patients 6 months of age and older. Ulesfia is available now by prescription nationwide in time for peak head lice season.
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A Combination Of Micronutrients Is Beneficial In Reducing The Incidence Of Prostate Cancer And Increasing Survival In The Lady Transgenic Model

UroToday.com - Dietary micronutrients are a common component of people"s diet as they seek to prevent cancer and other diseases. Micronutrients protect against cellular oxidative damage by neutralizing oxygen free radicals. In the May 2009 issue of Cancer Prevention Research, Dr. VasundaraVenkateswaran and associates tested the effects and timing of the micronutrients vitamin E (E), selenium (S), and lycopene (L) on the development of prostate cancer (CaP) in the Lady transgenic model. Transgenic male mice were randomized to the following groups; control diet, or control diet supplemented with a combination of E+S+L started at either 4, 8, 20, or 36 weeks of age. This experiment sought to investigate if the preventive effect of micronutrients was mediated by inhibiting cancer initiation or progression. Another experimental objective was to examine the micronutrients that were essentially contributing to this reduced incidence. To do this, transgenic male mice were randomized at 4 weeks of age to one of the following diets; control diet, control diet with a combination of E+S, and control diet supplemented with a combination of E+S+L. Mice were sacrificed and tissue and blood examined at 58 weeks of age. Weight gain was similar among groups. At 58 weeks of age there was a significant increase in the survival proportion of the animals in all of the intervention groups compared with the controls. Either E+S or E+S+L or diet supplemented with E+S+L initiated at 8, 20, and 36 weeks of age showed a significant increase in median survival compared with controls. Control mice would not be continued on the diet beyond 48 weeks of age due to tumor burden. Among control mice, 75% developed CaP and 16.7% high grade PIN. Only 10% of mice supplemented at 4 weeks of age with E+S+L developed tumors. Use of E+S+L when commenced by 8 weeks of age resulted in a highly significant reduction in CaP incidence. When micronutrients were commenced at 20 and 36 weeks of age, none of the mice had normal prostates. In control mice, liver metastasis were present in 75%, but in only 10% and 15.4% when micronutrients were started at 4 and 8 weeks, respectively. Early administration of micronutrients resulted in reduced the expression of proliferative marker PCNA and increased the extent of apoptosis. It also altered cell cycle regulation with up-regulation of the prognostic tissue marker p27kip1. Among all histologic, survival and molecular parameters assessed, it was apparent that lycopene was essential to the beneficial outcome. Despite the negative outcome of the SELECT trial, these data suggest that the early administration of micronutrients is important in experimental models. Venkateswaran V, Klotz LH, Ramani M, Sugar LM, Jacob LE, Nam RK, Fleshner NE Cancer Prev Res (Phila Pa). 2009 May;2(5):473-83 10.1158/1940-6207.CAPR-08-0124 Written by UroToday.com Contributing Editor Christopher P. Evans, MD, FACS UroToday - the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice. To access the latest urology news releases from UroToday, go to: www.urotoday.com Copyright © 2009 - UroToday


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