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Popular Articles

Obama Announces Regina Benjamin As Surgeon General Pick
Dr. Regina Benjamin is President Obama"s pick for surgeon general. The Alabama family physician has been an advocate for universal care, and is expected to have a role "at the table" in health reform, which would be an unusual degree of influence over policy for a surgeon general. Obama said Benjamin "represents what"s best about health care in America."

Too Early To Say If Screening Cuts Colon Cancer Deaths, Say Researchers
With more than 500,000 deaths each year, colorectal cancer is the third most common cause of deaths from cancer worldwide. Yet, despite a lack of evidence from randomised trials, many countries have launched large-scale colonoscopy screening programmes for the general population.
News of the day
Debate Over Taxing Health Benefits Picks Up
"As the debate on how to fix health care picks up pace, so does discussion about one of the most lucrative ways to pay for it:" taxing employer-provided health benefits, CNN reports. The "tax-free arrangement" in which an employer"s contribution to employee health benefit "is treated as tax-free to the employee in terms of income tax and payroll tax," was "born during the days of wage control in 1943." According to Paul Fronstin, director of the health research program at the Employee Benefit Research Institute, employers were not allowed to "attract workers on the basis of better pay," so instead they offered the benefits "as a way to compete for the best talent." Over the past 66 years, employees have come to expect it. But "tax and health experts say it"s inequitable. High-income workers and those with the most expensive health insurance plans enjoy the biggest break as a result of the tax exclusion."
Diagnostics

Clinical Trial Tests Protein To Reduce Angina Pain

As part of a multi-center clinical trial, UC San Diego Medical Center is evaluating the safety and effectiveness of a potential new way to treat angina by injecting a protein that stimulates the growth of new oxygen-rich blood vessels directly into the heart. Angina is a debilitating form of chest pain caused by coronary artery disease that affects more than nine million Americans. "This phase two clinical trial is testing whether or not a growth factor, injected into the heart muscle, is a safe way to initiate the growth a new network of blood vessels," said Anthony DeMaria MD, principal investigator of the trial and director of the Sulpizio Family Cardiovascular Center at UC San Diego Medical Center. "With a new of blood circulation, the goal is to reduce or eliminate attacks of angina." Described as squeezing pain or pressure, angina is caused by an insufficient blood supply to the heart. For some patients, the placement of a stent, or bypass surgery, may restore blood flow. Growth factor, a naturally occurring protein capable of stimulating cellular growth and proliferation, may one day offer a third treatment option for this condition. This placebo-controlled, double-blind study will evaluate the safety and tolerability of three different doses of a protein called human recombinant fibroblast growth factor-1. Eligible patients include males and females between the ages of 25 and 75 with a minimum three-month history of angina. The angina must be triggered by physical exertion and relieved by rest or nitroglycerin. Mkrtich Bandikian, the first California patient to participate in this trial, had quadruple bypass surgery more than a decade ago. He now suffers from angina if emotionally upset or during mild exercise such as walking. "I volunteered for the study for two reasons," said Bandikian. "Number one, I did this for myself. I like the idea of addressing the angina without surgery. Number two, if the doctors try this on me, and if the study helps another human being, why not let them try?" "My hope is that the angina pain will go down and that I will not have to take as much medication," added Bandikian. "I hope to be able to exercise again to raise my good cholesterol level." Before the protein is injected into the patient, a three-dimensional color-coded map is made of the patient"s heart using a technology called the NOGA XP Cardiac Navigation System. Guided by the map, Nabil Dib, MD, co-investigator of the trial, performs a one-hour procedure in which a catheter is threaded through the leg"s femoral artery and up into the heart. The protein is then injected into areas of the left ventricle that exhibit decreased blood flow. Patients who participate in this study are followed for a period of one year. Evaluations include exercise stress tests, nuclear imaging, electrocardiograms, and blood work. According to the American Heart Association, nearly 10 million people in the United States suffer from angina and an estimated 500,000 new cases of stable angina occur each year. Angina is a sign that someone is at increased risk of heart attack, cardiac arrest or sudden cardiac death. This clinical trial is sponsored by CardioVascular BioTherapeutics. Up to eight subjects will be recruited at UC San Diego Medical Center and more than two hundred nationwide. University of California, San Diego


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