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European Society Of Cardiology Congress 2009: 29 August To 2 September, 2009
The latest news on procedures, drugs and equipment in the field of cardiology will be presented at the European Society of Cardiology congress which will take place in Barcelona, from 29 August to 2 September.
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Gpx5: Sperm Shouldn't Leave The Testes Without This Protein
Joel Drevet and colleagues, at Clermont Universitç©, France, have identified a protein that helps protect immature mouse sperm after they have been released into a region of the testis known as the epididymis, which is where they undergo maturation. Although male mice lacking this protein, Gpx5, had normal looking sperm and were equally as efficient as normal male mice at fertilizing female mice, an increased incidence of miscarriages and fetal developmental defects were observed when normal female mice were mated with Gpx5-deficient males over 1 year old compared with normal male mice of the same age. Further analysis indicated that Gpx5 acts as an antioxidant in the epididymis, protecting the sperm from oxidative stress. As discussed by the authors, and, in an accompanying commentary, John Aitken, at the University of Newcastle, Australia, these data have immense clinical relevance as age-related DNA damage to human sperm has been associated with a range of adverse outcomes including decreased fertility, and increased rates of miscarriage and childhood disease.
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Medical Defence Union Supports Apologies To Patients But Says No Need For Duty Of Candour
Doctors already have a professional duty to provide patients with an explanation and apology when something goes wrong and the Medical Defence Union"s experience is that doctors do raise concerns and there is no need for a legal duty of candour. Each month the Medical Defence Union (MDU), takes several calls to its 24-hour advice line on the subject and opens files to assist medical members who want to raise concerns about patient safety.
Oncology

Government Targets Interfere With The Battle Against Superbugs, Says British Medical Association

The war on healthcare associated infections (HCAIs), or so-called "superbugs", will never be won unless long-term strategies are introduced to radically reduce their prevalence, says a BMA report launched recently. Short term solutions like alcohol gel, dress code and deep cleansing must be supplemented with sustainable evidence-based improvements that will protect more patients in the future, says the report. It adds, that without a change in direction the risk to patients caused by HCAIs and the burden on the NHS are set to continue. "Tackling healthcare associated infections through effective policy action" , a report produced by the BMA"s Board of Science, calls for a range of measures to minimise the spread of infection and strong governmental commitment focusing on long-term policies that tackle patient throughput and high bed occupancy. Dr Jonathan Fielden, Chairman of the BMA"s Consultants" Committee and a consultant in intensive care said: "Whilst we must congratulate NHS staff on their successful efforts to reduce HCAIs it is time to introduce longer-term solutions that are integrated and evidence-based. It"s not enough for politicians to announce new initiatives that are just sound bites. Genuine patient safety comes from embedding long-term strategies to tackle HCAIs. "Hygiene, hand-washing and antibiotic policies, have extremely important roles to play but if we want to reduce the spread of infections we must put safety in front of political targets. With many hospitals already working at full capacity, this will only get more pressurised as winter arrives. The pressure to turn around patients too quickly and the lack of adequate isolation facilities create critical challenges to maintaining high quality patient care. We want safe, timely care and treatment, not just fast care." The report says that overcrowding and understaffing in the UK healthcare system adversely impacts on infection control practices, including decreased hand hygiene, increased movement of staff and patients, and worse staff to patient ratios. These problems can only be addressed, according to the report, with strong organisational support that underpins the effective functioning of healthcare teams. The BMA"s Head of Science and Ethics, Dr Vivienne Nathanson, commented that: "With an ageing population and advances in medical technology and treatments, more patients are being treated than ever before and many are increasingly vulnerable to infection. Infection control is the responsibility of all, from the highest level of hospital organisation and management, to healthcare professionals, patients and visitors." Key areas for action outlined in the report include (see page 29 for a full list): - Reducing bed occupancy rates should be considered a priority in the development of policies relating to the number of available beds, admissions targets and bed management policies. - Effective workforce planning to ensure adequate staffing to match workload. - Dress code policies should be evidence-based with emphasis on the appropriate use of disposable protective clothing (eg gowns and gloves) when healthcare staff are exposed to potential contamination. - Adequate res should be provided for thorough everyday cleaning with an emphasis on cleaning high-risk near-patient hand-touch sites. - The introduction of screening policies should be evidence-based and take into account the practical and cost implications associated with the isolation of patients, visitors and staff who are carriers. - Compliance with hand hygiene protocols should be facilitated through education, motivation and improved access to hand washing facilities. - Strategies need to be developed for optimal antibiotic use. The British Medical Association


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