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Diabetes Specialists Call For Drug Regulators To Step In To Clarify Lantus Concerns, UK
BRITAIN"S top diabetes specialists added their weight to calls for European drug regulatory bodies to launch an urgent investigation into the popular insulin treatment glargine (Lantus). The move by the Association of British Clinical Diabetologists (ABCD) follows this week"s publication of four studies, which raise possible concern about an increased risk of the development of cancer in people who use this long-acting insulin therapy.
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Louisiana Cuts Rates For Medicaid Providers
"Louisiana will start paying less money Tuesday to many private health care providers for taking care of Medicaid patients, a move the state health department estimates will save $86 million this year," The Associated Press/The Advocate reports. Adults in the program may also have to pay a small co-pay if they visit emergency rooms for non-emergency care. "The cuts come as the health department shrinks its spending to $7.9 billion in the new fiscal year that began July 1, down $240 million from last year. Nearly all the cuts will be levied on the Medicaid program for the poor, elderly and disabled. But Jerry Phillips, state Medicaid director, said the department believes it can cover nearly two-thirds of that gap through efficiencies and the continuation of other cuts made during the last budget year."
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A New Regulator For Pharmacy, UK
A new, independent regulator for pharmacy professionals and pharmacy premises in Great Britain will be set up in spring 2010, Health Minister Mike O"Brien announced today.
Nutrition

Link Between Symptoms Of Depression In Obese Children And Elevated Cortisol

A new study connects abnormalities of the "stress" hormone cortisol with symptoms of depression in obese children, and confirms that obesity and depression often occur together, even in children. The results were presented at The Endocrine Society"s 91st Annual Meeting in Washington, D.C. "There is evidence in adults that abnormal regulation of cortisol plays a role in both obesity and depression," said the study"s lead author, Panagiota Pervanidou, MD, of Athens University Medical School in Athens, Greece. "Our study indicates that cortisol abnormalities may underlie obesity and depression starting in childhood." Cortisol is a steroid hormone that helps the body respond to stress but also has other functions, including converting fat, protein and carbohydrates into energy. Normally, levels of this hormone peak in the early morning, start to drop in late morning and reach their low point at night. However, depressed adults have slightly elevated cortisol levels at night - "the endocrine equivalent of chronic stress," Pervanidou said. This chronic elevation of cortisol contributes to development of the metabolic syndrome, which includes abdominal obesity and other risk factors for diabetes and cardiovascular disease. In this new study, Pervanidou and colleagues measured cortisol five times a day in the saliva of 50 obese children and teenagers as well as in their blood in the morning. The 20 boys and 30 girls, ages 8 to 15 years, were patients in the Athens University pediatric obesity clinic and did not have a prior diagnosis of depression. All subjects completed the Children"s Depression Inventory (CDI), a questionnaire that assesses self-reported symptoms of depression. Cortisol levels in the saliva in the afternoon and evening correlated positively with symptoms of depression, the authors reported. The more depressive symptoms that subjects reported, the higher the cortisol levels at those times. This finding indicates that obesity and depression may not only be related to behavior but also may have a hormonal link, according to Pervanidou. Because obesity and depression often co-occur, she said that prevention and screening should focus on both disorders and should start in childhood. "We recommend that obese children be screened for depression and anxiety, especially female adolescents, who have the highest risk," she said. "In addition, children with a diagnosis of depression should be evaluated for disordered eating, because these patients frequently develop obesity or anorexia." Aaron Lohr The Endocrine Society


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