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Vaxart Begins Animal Testing Of H1N1 Flu Vaccine Candidate
Vaxart, Inc., a biotechnology company focused on the development of oral vaccines, announced today that the company has created a candidate vaccine for H1N1 influenza (swine flu). On Saturday, May 23, Vaxart began testing for immune responses in animals, just 25 days after initiating the project. The company will compare performance of the research-grade H1N1 vaccine to its successful avian flu vaccine as a first step towards potential human clinical testing.

Prostate Cancer Screening And Trust Of Physician Evaluated
Trusted health care s and continuity of care may help reduce the risk of prostate cancer deaths in African-American men, according to a study published in the current issue of the journal Cancer. James Mohler, MD, Chair of the Department of Urology at Roswell Park Cancer Institute (RPCI), and William R. Carpenter, PhD, Department of Health Policy and Management at the University of North Carolina, are lead investigators.
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New Analysis Shows Efficacy Of SIMPONI(TM) (golimumab) In Anti-TNF Experienced Rheumatoid Arthritis Patients
A new analysis demonstrated that a greater proportion of patients with moderately to severely active rheumatoid arthritis (RA) who had prior treatment with anti-tumor necrosis factor (TNF)-alpha agents and received subcutaneous injections of SIMPONI(TM) (golimumab) once every four weeks experienced significant improvements in signs and symptoms through week 24, compared with patients receiving placebo. Patients continued to receive stable doses of methotrexate, sulfasalazine and/or hydroxychloroquine if receiving them at baseline. These data were presented at the 2009 European League Against Rheumatism (EULAR) Annual Congress.
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Making Waves: LSU's WAVCIS Increases Modeling Capabilities

LSU"s WAVCIS, or Wave-Current-Surge Information System for Coastal Louisiana, has a few new tricks up its sleeve in preparation for the 2009 hurricane season. Drawing from a pool of scientific talent at the university, across the nation and Europe, WAVCIS now offers graphic, easy-to-understand model outputs projecting wave height, current depths and tracks, salinity ratios and water temperature measurements that not only provide state-of-the-art guidance to emergency management officials, but also give federal and state agencies such as the United States Navy, National Oceanic and Atmospheric Administration, the National Weather Service, National Hurricane Center and Louisiana Department of National Res new and improved ways to test their own modeling accuracy. "I believe WAVCIS is likely the most comprehensive program in the entire nation," said Gregory Stone, director of both the WAVCIS program and the Coastal Studies Institute and also the James P. Morgan Distinguished Professor at LSU. "We now have 60 to 84 hour advance forecasting capabilities due to our satellite link-ups with NOAA and our supercomputing capabilities. Because of these advancements, we are in much better shape for the 2009 hurricane season to provide valuable information than we were in the past." WAVCIS operates by deploying equipment in the depths of the Gulf of Mexico. Currently, they have sensors attached to numerous oil platforms. Instruments are attached to towers on the platforms and allow meteorological measurements - air temperature, wind speed and direction, visibility - to be made; state-of-the-art oceanographic sensors are placed underwater and on the sea floor. Advanced technology, including the Acoustic Doppler Profiler, an instrument that Stone"s group has helped perfect in real time with the private sector, provides a very comprehensive overview of current velocities from the sea bed to the surface in addition to wave conditions on the sea surface. "In a normal weather situation, WAVCIS links with the satellites and retrieves up-to-date information every hour. This information is then immediately supplied to computer models at LSU"s WAVCIS lab and the data are posted on the WAVCIS Web site," said Stone. "However, during a hurricane or other extreme weather events, we have the capacity to increase the frequency of these link-ups. We won"t have the luxury of waiting an hour during the approach of a hurricane - it"s critical that we can see what"s going on out there in 15 to 30 minute intervals in order to accurately assess the situation." The WAVCIS group, a component of LSU"s world famous Coastal Studies Institute, has sensors all throughout the Gulf of Mexico. In fact, most of the equipment used by WAVCIS is developed and maintained in-house at the Coastal Studies Institute"s fabrication shop. Through a close and reciprocal relationship with NOAA"s National Data Buoy Center, WAVCIS can also access that group"s sensors, giving the system a gulf-wide look at emerging trends in waves and currents, which can be very important during the approach of a tropical cyclone. "Things such as the maximum wave height, wind speeds and storm surge, will play an integral role in issues concerning public safety," said Stone. "For example, the development of certain currents, such as the Loop current in the Gulf of Mexico, allows for almost immediate intensification of storms. That"s why having an easy-to-understand and comprehensive end product was so important to my team and the Coastal Studies Institute, for example the Earth Scan Lab and the Southern Regional Climate Center, during the development stages. When it"s crunch time and people are nervous, we want the facts to be clear." In addition to being a very active research group and providing graduate and undergraduate students with hands-on opportunities in an internationally-acclaimed lab, WAVCIS also provides other entities with the opportunity to test their own modeling accuracy. "By looking at the models they developed and then comparing them to ours and our measurements offshore, they can determine how accurate their models currently are and go about fine-tuning if necessary. This strengthens our knowledge of the oceanographic and coastal environment. Given the vulnerability of, for example coastal Louisiana and the oil and gas infrastructure in the Gulf of Mexico to erosion and hurricane impacts, it is important that the Federal Government, State of Louisiana and the oil and gas industry continue to support this effort," Stone said. WAVCIS models are available on http://wavcis.csi.lsu.edu/index.asp. Ashley Berthelot Louisiana State University


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