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Popular Articles

Lobbyists Elbow For Attention As Health Reform Votes Loom
The conservative message on health care is that President Obama"s revamp of the health care system in America will produce a costly government-run program that limits patient choice, The Associated Press reports.

Two Types Of Urgency - Overactive Bladder - Urgency Is Not Just Urgency
UroToday.com - "Urgency" is the cornerstone of the diagnosis of overactive bladder (OAB) as well as a common complaint of patients with BPS/IC. What the term actually refers to when used by patients remains problematic and the subject of some controversy. The International Continence Society defines it as a "sudden compelling desire to void that is difficult to defer". The word sudden is designed to differentiate the sensation from the "urgency" that patients with BPS/IC complain of, but the distinction is quite vague in practice. Many believe that it is the reason for the urgency (fear of incontinence vs. pain) that should make the distinction.
News of the day
New Survey: Health Care Leaders Say Need For Reform Is Urgent; Broadly Support Public Health Care Option, Provider Payment Reform
By a wide margin, health care leaders believe that individuals should have a choice of public and private health plans, and strongly support other central components of health reform such as innovative provider payment reform and a national insurance health exchange with strong standard-setting authority. In addition, two-thirds (68%) of opinion leaders feel it is urgent to enact comprehensive health care reform this year, according to the latest Commonwealth Fund/Modern Healthcare Health Care Opinion Leaders Survey.
Endocrinology

Scripps Discovers Genetic Clues Into Formation Of Cancer Tumors

A new research study from Scripps Health provides previously unknown genetic clues into how cancerous tumors are formed in the human breast, brain and colorectal system. The findings by researchers at Scripps Translational Science Institute (STSI) will be published in the September 2009 edition of the journal Genome Research. STSI researchers analyzed genetic data from 44 breast cancer, colorectal cancer and glioblastoma tumors and identified specific mutations within groups of genes that are strongly involved in tumor formation. A mutation is a change in a cell"s DNA. While a large number of mutations occur within any tumor, not all of them contribute directly to the tumor"s growth. Some mutations are akin to "random noise" while other mutations cause a growth advantage for tumors. The STSI study differentiated between the random and causative mutations. "Understanding which specific mutations cause a tumor to form is an important step that may potentially translate into a more personalized approach to treating cancer patients," said Ali Torkamani, Ph.D., an STSI research scientist and the study"s principal investigator. "These mutations provide us with targets for drug development that presumably would be more efficient at killing cancer, with lower toxicity levels that are safer for patients." The new study builds upon earlier research conducted by Johns Hopkins University scientists, who sequenced cancerous tumors and studied individual genes linked to tumor growth. Because there are many different ways a tumor can be formed, STSI designed its research to look at groups of genes. Torkamani co-authored the study with Nicholas Schork, Ph.D., director of bioinformatics and biostatistics for STSI. Scripps Translational Science Institute


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