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Study Links Recurrence Of Abnormal Cervical Cells To Age, Treatment Type
Older women, women with a higher grade of precancerous cells and women who undergo a freezing procedure known as cryotherapy to remove abnormal cervical cells are at a higher risk than other groups that the problem cells will return or develop into cervical cancer, according to a study published in the Journal of the National Cancer Institute, Reuters reports. For the study, Joy Melnikow of the University of California-Davis and colleagues compared 37,000 women who were treated for cervical intraepithelial neoplasia -- abnormal cervical cells -- from 1986 through 2000 with 71,000 women who had no history of abnormal cervical cells.The researchers found that the risk of cervical cancer and recurrence of medium to severe degrees of CIN was highest for women who were older than age 40, who had been previously treated for severe CIN or whose abnormal cells were treated using cryotherapy. The women underwent cone biopsies a surgical procedure to remove abnormal cells were least likely to have a recurrence of CIN. According to Melnikow, recurrence was most likely to occur within the first six years after treatment. Melnikow said that women who have been treated surgically have higher risks of bleeding and preterm labor. Therefore, younger women who are planning to become pregnant might prefer cryotherapy, she said, adding that younger women"s "risk of recurrence is lower, and a recurrence can be treated again" (Steenhuysen, Reuters, 5/12).

Parent's Guide To Cord Blood Foundation Introduces New Brochure During Cord Blood Awareness Month To Address Critical Education Gap
Expectant parents are poorly informed about cord blood banking, according to a study published in the Journal of Reproductive Medicine. In fact, of the expectant mothers in the study who indicated they have some knowledge of cord blood banking, 74 percent considered themselves minimally informed. Yet, the Institute of Medicine of the National Academy of Sciences recommends that all expectant parents should be educated about cord blood stem cells early enough in pregnancy that they can make an informed decision about the options to preserve these medically-beneficial cells.
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'Hijacking Mechanism' Of HIV-1' Pinpointed By McGill/JGH Researchers
Researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal"s Jewish General Hospital - along with colleagues at the University of Manitoba and the University of British Columbia - may have found a chink in the armour of the human immunodeficiency virus type 1 (HIV-1), the microorganism which causes AIDS. They have pinpointed the key cellular machinery co-opted by HIV-1 to hijack the human cell for its own benefit. Their study was published in May in the Journal of Biological Chemistry.
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Study Shows The Negative Side To Positive Self-Statements In Self-Help Books

In times of doubt and uncertainty, many Americans turn to self-help books in search of encouragement, guidance and self-affirmation. The positive self-statements suggested in these books, such as "I am a lovable person" or "I will succeed," are designed to lift a person"s low self-esteem and push them into positive action. According to a recent study in Psychological Science, a journal of the Association for Psychological Science, however, these statements can actually have the opposite effect. Psychologists Joanne V. Wood and John W. Lee from the University of Waterloo, and W.Q. Elaine Perunovic from the University of New Brunswick, found that individuals with low self-esteem actually felt worse about themselves after repeating positive self-statements. The researchers asked participants with low self-esteem and high self-esteem to repeat the self-help book phrase "I am a lovable person." The psychologists then measured the participants" moods and their momentary feelings about themselves. As it turned out, the individuals with low self-esteem felt worse after repeating the positive self-statement compared to another low self-esteem group who did not repeat the self-statement. The individuals with high self-esteem felt better after repeating the positive self-statement - but only slightly. In a follow-up study, the psychologists allowed the participants to list negative self-thoughts along with positive self-thoughts. They found that, paradoxically, low self-esteem participants" moods fared better when they were allowed to have negative thoughts than when they were asked to focus exclusively on affirmative thoughts. The psychologists suggested that, like overly positive praise, unreasonably positive self-statements, such as "I accept myself completely," can provoke contradictory thoughts in individuals with low self-esteem. Such negative thoughts can overwhelm the positive thoughts. And, if people are instructed to focus exclusively on positive thoughts, they may find negative thoughts to be especially discouraging. As the authors concluded, "Repeating positive self-statements may benefit certain people [such as individuals with high self-esteem] but backfire for the very people who need them the most." Katie Kline Association for Psychological Science


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