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Inovio Biomedical Universal Dengue DNA Vaccine Demonstrates Strong Immune Responses Against All Four Serotypes
Inovio Biomedical Corporation (NYSE Amex: INO), a leader in DNA vaccine design, development and delivery, announced that the company"s first SynCon™ dengue virus DNA vaccine induced neutralizing antibody responses against all four distinct serotypes of dengue viruses that are transmitted to humans by mosquitoes. Currently there is no commercially available vaccine or antiviral drug against dengue virus infections. The results were published in Vaccine, July 3, 2009, in a paper entitled, "Development of a novel DNA SynCon tetravalent dengue vaccine that elicits immune responses against four serotypes" (Ramanathan MP, Kuo YC, Selling BH, Li Q, Sardesai NY, Kim JJ, Weiner DB).

Elsevier's PharmaPendium Introduces The FDA Classic Collection
PharmaPendium, Elsevier"s online re for authoritative preclinical, clinical and post-marketing drug information, has significantly expanded its coverage of US Food and Drug Administration (FDA) approval documents with the launch of the FDA Classic Collection. This collection contains all available historical FDA approval documents up to and including those issued in 1991 - all indexed and made searchable for the first time in history. With the addition of the FDA Classic Collection, PharmaPendium has become the only integrated, searchable of all FDA drug approval documents.
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Illinois Counties Facing Increases In STDs Among Teenagers; Bill Aims To Reduce Rates
Illinois health officials contend that images seen in the media, social influences, and a lack of "frank" discussion on STDs in schools, among other issues, might be contributing to increases in STD rates across the state, the State Journal-Register reports. "According to recently released data, new cases of chlamydia in Illinois reached an all-time high statewide in 2008 - 59,169 - while the number of gonorrhea cases outside Chicago has been rising in recent years and totaled 10,165 in 2008," the Journal-Register reports. In addition, about 35,000 state residents have HIV/AIDS, the article states. Charlie Rabins, chief of the STD program at the Illinois Department of Public Health, said a bill (SB 212) currently awaiting Gov. Pat Quinn"s (D) approval might help reduce STD rates. The bill "would allow what is called "expedited partner therapy," in which medical professionals who treat patients for gonorrhea or chlamydia can give those patients single-dose antibiotics to pass on to sexual partners without first examining the partners," according to the Journal-Register (Olsen, 7/27).
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U.N. Secretary-General, WHO Director-General Appeal For Continued Investment In Global Health

Despite the current global economic crisis, U.N. Secretary-General Ban Ki-moon on Monday called for a continued international commitment to investing in health, Xinhua/People"s Daily reports. "We can cut back on health expenditures and incur massive losses in lives and fundamental capacity for growth. Or we can invest in health and spare both people and economies the high cost of inaction," Ban said during an address at the U.N. Forum on Advancing Global Health in the Face of Crises, a day-long forum at U.N. headquarters in New York. "The cost of cutting back is just unthinkable" (Xinhua/People"s Daily, 6/16). WHO Director-General Margaret Chan told the forum "that developing countries are most vulnerable to the global H1N1 (swine) flu epidemic, the financial crisis, food shortages and climate change - and much more must be done to urgently strengthen their health care systems," the AP/Washington Post reports. "Because of the economic downturn, people in affluent societies are losing their jobs, their homes, and their savings, and this is tragic," Chan said. "In developing countries, they will lose their lives" (Lederer, AP/Washington Post, 6/16). "We need to heed the call of our conscience, recognize that our interests are bound together, and act - united - with the urgency the times demand," Ban said, pointing to the H1N1 pandemic as "a reminder of our global vulnerability and the need for a global response," ISRIA writes. "We cannot protect ourselves by working in isolation," Ban said. "This is as true for the recent outbreak as it is for the long-standing health challenges we face" (ISRIA, 6/15). Chan noted that pregnancy and underlying health conditions increase the morbidity and mortality for those infected with the H1N1 virus, and that the majority of maternal deaths and chronic diseases occur in low- and middle-income countries. "I firmly believe that this pandemic will reveal, in a highly visible, measurable and tragic way, exactly what it means, in life-and-death terms, when health needs and health systems have been neglected, for decades, in large parts of the world," Chan said. "We will see, in extremely tragic ways, the consequences of our longstanding failure to ensure basic care during pregnancy and childbirth," she said (AP/Washington Post, 6/16). "Developing countries have the greatest vulnerability and the least resilience. They will be hit the hardest and take the longest to recover," Chan said, adding, "In terms of measures to mitigate the health impact, many poor countries are virtually empty-handed." Chan "urged senior government officials to place "fairness" at the core of decisions to protect the most vulnerable against major worldwide crises," Xinhua reports (Xinhua, 6/15). "Greater equity in the health status of populations, within and between countries should be regarded as a key measure of how we, as a civilized society, are making progress," Chan said. Ban also called for an international response to maternal and child health worldwide, AFP/Google.com reports. "The global impact of maternal and newborn deaths has been estimated at 15 billion dollars a year in lost productivity," Ki-moon said. "We must use maternal health as a lens through which we decide and act on global health policies" (AFP/Google.com, 6/15). NPR"s Morning Edition examines international efforts to protect the health needs of mothers and children in developing countries. According NPR, "Ban called on donors to honor existing commitments to the Millennium Development Goals, pledges that amount to $20 billion between 2007 and 2015 an amount totaling $20 billion between 2007 and 2015" (Wilson, NPR, 6/15). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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