Popular Articles

NICE Recommends Use Of Cetuximab (Erbitux(R)) For UK Bowel Cancer Patients
The National Institute for Health and Clinical Excellence (NICE) has today published a Final Appraisal Determination (FAD) recommending the use of the drug cetuximab (Erbitux®) in combination with chemotherapy as a 1st-line treatment for patients with metastatic (advanced) colorectal cancer (mCRC) who have met specific additional criteria1* - presenting the possibility of potentially curative surgery.2 The treatment is recommended for patients in whom the cancer has spread only to the liver and who have "wild-type" (unmutated) KRASò€¡ tumours.1 Up to 65% of patients have wild-type KRAS tumours.3

Discovery May Revolutionize Therapy In Muscular Dystrophy And Other Skeletal Muscle Disorders
Researchers at UMDNJ-Robert Wood Johnson Medical School are a step closer to treating, and perhaps preventing, muscle damage caused by disease and aging. In their study, published in the June issue of Journal of Biological Chemistry, the scientists have linked the newly discovered protein MG53 to a pathway that repairs human muscle tissue along with the proteins caveolin-3 (Cav3) and dysferlin. Prior to this study, the underlying interactions that inhibited membrane repair in muscle tissue were unknown. Linking these proteins creates a mechanism that allows damaged membranes to be repaired, which may transform treatment for patients who suffer from severe complications of diseases such as muscular dystrophy, as well as cardiovascular disorders and conditions related to advancing age.
News of the day
UPMC South Hills Making Something Healthy Happen
UPMC South Hills will host a free health fair from 11 a.m. to 2 p.m., Saturday, June 13, at 1300 Oxford Drive, just across from Village Square Mall in Bethel Park.
Nutrition

Women With Stable Marriages And New Partners Enjoy Better Sleep

Women who have stable marriages or who have recently gained a partner reported better sleep than women who are unmarried or who have lost a partner, according to a new University of Pittsburgh study. To assess the effects of marital stability and relationship changes on sleep, the study"s lead author, Wendy Troxel, Ph.D., assistant professor of psychiatry at Pitt"s School of Medicine, examined data from 360 middle-aged Chinese, Caucasian and African-American women over eight years. The researchers found that women who were in a stable marriage had the highest quality sleep measured objectively and subjectively, and these results persisted even after controlling for other known risk factors for sleep, including age, ethnicity, socioeconomic status and depressive symptoms. University of Pittsburgh


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